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KMID : 0375219950100010069
Journal of Il Sin Christian Hospital
1995 Volume.10 No. 1 p.69 ~ p.76
Clinical Study of Cervical Intraepithelial Neoplasm
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Abstract
Colposcopic examination and biopsy were performed on 197 patients with abnormal cervical cytology.
The patients subsequently underwent electrocoagulation, LLETZ, conization and hysterectomy depending on their diagnosis from January, 1989 to December, 1994.
The comparison between the diagnosis of cytology and that of colposcopic biopsy showed fair agreement with only 35% of cases(k=20%). The abnormal lesion was underestimated by cytology in 49.7% of cases.
Thirty three cases(16.8%) were treated by LLETZ. Histological comparison between the colposcopic biopsies and LLETZ samples showed fair agreement with 39% of cases(k=25%). 5 cases(15%) of the colposcopic biopsy have been underestimated when
compared to
the LLETZ histology.
Sixty two cases were done conization after colposcopic biopsy. Histological comparison between the colposcopic biopsies and conization samples showed fair agreement with 59% of cases(K=38%). The colposcopic biopsies were underestimated in 24.2%
of
cases
compared to the cone biopsy specimen. The correct diagnosis rates of colposcopic biopsy of dysplasia, carcinoma in situ, an dmicroinvasive carcinoma were 70%, 82%, and 20% respectively.
Of the 62 conizations, 53 cases(85.5%) had clear margins and 9 cases(14.5%) had involved margins.
Residual tumors were found in subsequent hysterectomy specimens in 10 of 44 cases923%). 8 cases of these, residual tumors were same pathologic grade and 1 case was more severe pathologic grade.
Eighty eight cases(44.7%) were treated by hysterectomy after colposcopic biopsy without conization. Histological comparison between the colposcopic biopsies and hysterectomy samples showed fair agreement with 44.3% of cases (K=22%) and diagnostic
accuracy of colposcopic biopsy was 625% within one grade.
KEYWORD
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